Lysianadioic acid, a carboxypeptidase B inhibitor from Lysiana subfalcata.
نویسندگان
چکیده
A new natural product, lysianadioic acid, was isolated from the plant Lysiana subfalcata as a carboxypeptidase B (CPB) inhibitor. It is a potent inhibitor of CPB with an IC(50) of 0.36 microM. This is the first known example of a small molecule CPB inhibitor isolated from plant origin. Its structure was determined by NMR spectroscopy.
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عنوان ژورنال:
- Bioorganic & medicinal chemistry letters
دوره 18 4 شماره
صفحات -
تاریخ انتشار 2008